產品名稱:PE 小鼠抗人 CD138 抗體;PE Mouse Anti-Human CD138
中文名稱:PE Mouse Anti-Human CD138
英文名稱:PE Mouse Anti-Human CD138
PE Mouse Anti-Human CD138 產品介紹:
Material Number: 550805 Alternate Name: Syndecan-1 Size: 100 tests Vol. per Test: 20 μl Clone: DL-101 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: NA Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Mouse Anti-Human CD138 Description:
Reacts with CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, expressed on multiple myeloma-derived cell lines and malignant plasma cell populations. It is also expressed on pre-B cells, immature B cells and plasma cells, but not on mature circulating B-lymphocytes. Syndecan-1 is a member of the family of transmembrane heparan sulfate proteoglycans. It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells. CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III and V, tenascin, thrombospondin, and antithrombin III. It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules. Monoclonal antibody DL-101 does not block the binding of clone B-B4 (another anti-syndecan-1 antibody) or Mi15 by flow cytometric analysis.
PE Mouse Anti-Human CD138 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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