PE Mouse Anti-Human CD16b

產品名稱:PE 小鼠抗人 CD16b 抗體；PE Mouse Anti-Human CD16b

中文名稱:PE 小鼠抗人 CD16b 抗體

英文名稱:PE Mouse Anti-Human CD16b

PE Mouse Anti-Human CD16b 產品介紹：

Material Number: 550868
Size: 100 tests
Vol. per Test: 20 μl
Clone: CLB-gran11.5
Isotype: Mouse IgG2a, κ
Reactivity: QC Testing: Human
Workshop: IV N404
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

PE Mouse Anti-Human CD16b Description：

Reacts with CD16b, a glycosyl phosphatidyl inositol-anchored (GPI) protein expressed on human neutrophils. Human CD16 is the low
affinity Fc gamma receptor III (Fc gamma RIII) and shows two distinct forms coded by two linked genes. One form is CD16a, a polypeptide-anchored form (Fc gamma RIIIA), present on natural killer cells and macrophages. The other form is CD16b the GPI-anchored form, Fc gamma RIIIB, found on human neutrophils. CD16b is polymorphic and the two codominant alleles are referred to as Neutrophil Antigen 1 (NA1) and Neutrophil Antigen 2 (NA2). Clone CLBgran11.5 reacts with neutrophils expressing the NA1 molecule. CD16b has been reported to participate in immune complex binding by resting neutrophils and also in neutrophil transendothelial migration by interacting with integrins during the inflammation response process.

PE Mouse Anti-Human CD16b Preparation and Storage：

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.