PE Rat Anti-Mouse Vβ 11 T-Cell Receptor

產品名稱:PE 大鼠抗小鼠 Vβ 11 T-Cell Receptor 抗體；PE Rat Anti-Mouse Vβ 11 T-Cell Receptor

中文名稱:PE 大鼠抗小鼠 Vβ 11 T-Cell Receptor 抗體

英文名稱:PE Rat Anti-Mouse Vβ 11 T-Cell Receptor

PE Rat Anti-Mouse Vβ 11 T-Cell Receptor 產品介紹：

Material Number: 553198
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: RR3-15
Immunogen: Mouse Cytolytic T-Cell Clone OH6
Isotype: Rat (F344) IgG2b, κ
Reactivity: QC TEsting: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.



PE Rat Anti-Mouse Vβ 11 T-Cell Receptor Description：

The RR3-15 antibody reacts with the Vβ 11 T-Cell Receptor (TCR) of mice having the b haplotype (e.g., A, C57BL, C58, DBA/1) of the Tcrb 
gene complex. The Tcrb-V11 gene locus is deleted in mice having the a (e.g., C57BR, C57L, SJL, SWR) and c (e.g., RIII) haplotypes. Vβ 
TCR-bearing T lymphocytes are clonally eliminated in mice expressing I-E and superantigens encoded by Mtv-9 (Etc-1, Mls[f], Dvb11.2) 
and/or Mtv-11 (Mls[f], Dvb 11.2) proviruses (e.g., AKR, BALB/c, CBA/J, C3H, DBA/2), and they are incompletely eliminated in mice 
expressing I-E and Mtv-8 (Mls[f], Dvb 11.1) superantigen (e.g., A). Activation of Vβ 11 TCR-expressing T cells by these determinants is 
dependent upon presentation by I-E. The bacterial superantigen Staphylococcal enterotoxin A (SEA) also interacts with Vβ 11 TCR, and in 
vivo exposure to SEA causes activation and subsequent deletion of Vβ TCR-expressing lymphocytes. Plate-bound RR3-15 antibody activates 
Vβ 11 TCR-bearing T cells

PE Rat Anti-Mouse Vβ 11 T-Cell Receptor Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed by gel 
filtration chromatography.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.