產品名稱:FITC 大鼠抗小鼠 CD107a 抗體;FITC Rat Anti-Mouse CD107a
中文名稱:FITC 大鼠抗小鼠 CD107a 抗體
英文名稱:FITC Rat Anti-Mouse CD107a
FITC Rat Anti-Mouse CD107a 產品介紹:
Material Number: 553793 Alternate Name: LAMP-1 Size: 0.5 mg Concentration: 0.5 mg/ml Clone: 1D4B Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line Isotype: Rat (SD) IgG2a, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
FITC Rat Anti-Mouse CD107a Description:
The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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