產品名稱:PE 大鼠抗小鼠 CD1d 抗體;PE Rat Anti-Mouse CD1d
中文名稱:PE 大鼠抗小鼠 CD1d 抗體
英文名稱:PE Rat Anti-Mouse CD1d
PE Rat Anti-Mouse CD1d 產品介紹:
Material Number: 553846 Alternate Name: CD1.1, Ly-38 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: 1B1 Immunogen: Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma and mouse L929 cells Isotype: Rat (LEW) IgG2b, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. PE Rat Anti-Mouse CD1d Description:
The 1B1 antibody reacts with CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I molecules. The structure, expression, and functions of CD1 antigens are complex and have been reviewed. mAb 1B1 detects CD1d at varying levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus. It appears to recognize CD1d only in association with β2m. CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the cytoplasm of hepatocytes as detected viaimmunohistochemical staining of frozen sections with mAb 3C11 (Cat. No. 559871, for the purified antibody), suggesting a possible role for CD1d in mucosal immunity. However, CD1d expression was not detectable, via flow cytometry, on intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1, and 9C7. The 1B1 antibody competes with mAb 3C11 in binding to mouse splenocytes.
PE Rat Anti-Mouse CD1d Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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