產品名稱:Purified 倉鼠抗小鼠 CD95 抗體;Purified Hamster Anti-Mouse CD95
中文名稱:Purified 倉鼠抗小鼠 CD95 抗體
英文名稱:Purified Hamster Anti-Mouse CD95
Purified Hamster Anti-Mouse CD95 產品介紹:
Material Number: 554255 Alternate Name: Fas/APO-1 Size: 0.5 mg Concentration: 0.5 mg/ml Clone: Jo2 Immunogen: WR19L mouse lymphoma cells transformed with recombinant mouse Fas Isotype: Armenian Hamster IgG2, λ2 Reactivity: QC Testing: Mouse Target Molecular Weight: 45 kDa Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Purified Hamster Anti-Mouse CD95 Description:
Fas antigen, CD95, is a 45 kDa cell-surface protein which can mediate apoptosis. It belongs to the TNF (tumor necrosis factor)/NGF receptor family. Expression of Fas has been described in the thymus, liver, heart, lung and ovary. Fas plays an important role in the apoptotic process that takes place during development. Monoclonal antibodies recognizing Fas such as Jo2 have cytolytic activity on cells expressing Fas. The cell death stimulated by Fas antibodies is characteristic of apoptosis and suggests that the lethal effects are a result of interaction of antibody with a functional Fas antigen as opposed to complement-mediated lysis.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4° C.
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