Purified Mouse Anti-Human Disialoganglioside GD2

產品名稱:Purified 小鼠抗人 Disialoganglioside GD2 抗體；Purified Mouse Anti-Human Disialoganglioside GD2

中文名稱:Purified 小鼠抗人 Disialoganglioside GD2 抗體

英文名稱:Purified Mouse Anti-Human Disialoganglioside GD2

Purified Mouse Anti-Human Disialoganglioside GD2 產品介紹：

Material Number: 554272
Alternate Name: GD2
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: 14.G2a
Immunogen: LAN-1 human neuroblastoma cells
Isotype: Mouse (BALB/c) IgG2a
Reactivity: QC Testing: Human
Tested in Development: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


Purified Mouse Anti-Human Disialoganglioside GD2 Description：

Gangliosides are sialic-acid bearing glycolipids that are expressed on the surface of all mammalian cells, and are likely involved in mediating
cell-substratum interactions. They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and
neuroblastoma cells. Human melanoma cells produce gangliosides, designated as GD2 and GD3 which are deposited in the subtratum-attached
material, and may play a significant role in the melanoma metastatic phenotype. Clone 14.G2a specifically reacts with human and mouse GD2
ganglioside. LAN-1 human neuroblastoma cells were used as immunogen. Clone 14.G2a is an isotype switch variant selected from the
parental IgG3-producing hybridoma 14.18 and has identical reactivity as the parental antibody. Clone 14.G2a is routinely tested by flow
cytometry using M21 human melanoma cells.

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.