產品名稱:PE 大鼠抗小鼠 IL-2 抗體;PE Rat Anti-Mouse IL-2
中文名稱:PE 大鼠抗小鼠 IL-2 抗體
英文名稱:PE Rat Anti-Mouse IL-2
PE Rat Anti-Mouse IL-2 產品介紹:
Material Number: 554428 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: JES6-5H4 Immunogen: Mouse IL-2 Recombinant Protein Isotype: Rat IgG2b Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PE Rat Anti-Mouse IL-2 Description:
The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2Rβ (CD122) and common gamma chain (γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2Rα (CD25), IL-2Rβ and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.
PE Rat Anti-Mouse IL-2 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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