產品名稱:APC 大鼠抗小鼠 IL-2 抗體;APC Rat Anti-Mouse IL-2
中文名稱:APC 大鼠抗小鼠 IL-2 抗體
英文名稱:APC Rat Anti-Mouse IL-2
APC Rat Anti-Mouse IL-2 產品介紹:
Material Number: 554429 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: JES6-5H4 Immunogen: Mouse IL-2 Recombinant Protein Isotype: Rat IgG2b Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide APC Rat Anti-Mouse IL-2 Description:
The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2Rβ (CD122) and common gamma chain (γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2Rα (CD25), IL-2Rβ and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.
APC Rat Anti-Mouse IL-2 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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