APC Rat Anti-Mouse IL-10

產品名稱:APC 大鼠抗小鼠 IL-10 抗體；APC Rat Anti-Mouse IL-10

中文名稱:APC 大鼠抗小鼠 IL-10 抗體

英文名稱:APC Rat Anti-Mouse IL-10

APC Rat Anti-Mouse IL-10 產品介紹：

Material Number: 554468
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: JES5-16E3
Immunogen: Recombinant mouse IL-10
Isotype: Rat IgG2b
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The JES5-16E3 monoclonal antibody specifically binds to the mouse cytokine, Interleukin-10 (IL-10). IL-10 is also known as Cytokine 
Synthesis Inhibitory Factor (CSIF). It is produced by various activated cell types including CD4+ T cells, CD8+ T cells, NK T cells, B1 B 
cells, NK cells, macrophages, dendritic cells, mast cells, granulocytes and keratinocytes. IL-10 plays a pivotal role in regulating immune 
responses and protecting the host from damage caused by inflammatory and autoimmune responses. IL-10 has numerous biological activities 
including the inhibition of cytokine synthesis by activated T cells, NK cells, monocytes, and macrophages. In the presence of accessory cells, 
IL-10 inhibits mitogen- or anti-CD3 induced proliferation of T lymphocytes. IL-10 has also been shown to costimulate the development of 
thymocytes, B cell differentiation and the generation of cytotoxic T cells. The immunogen used to generate the JES5-16E3 hybridoma was 
recombinant mouse IL-10. JES5-16E3 is a neutralizing antibody.

APC Rat Anti-Mouse IL-10 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.