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Recombinant Human IL-12 (p70)

產品名稱: Recombinant Human IL-12 (p70)
產品型號: BD-554613
產品展商: BD Pharmingen
產品文檔: 無相關文檔

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Recombinant Human IL-12 (p70)  的詳細介紹

產品名稱:Recombinant Human IL-12 (p70)

Recombinant Human IL-12 (p70) 產品介紹:

Material Number: 554613
Size: 5 μg
Concentration: 100 μg/ml
Reactivity: QC Testing: Human
Storage Buffer: Frozen aqueous buffered solution containing BSA and glycerol.

Recombinant Human IL-12 (p70) Description:

Interleukin-12 (IL-12) is a potent regulator of cell-mediated immune responses. Biologically active IL-12 is secreted by activated B
lymphocytes and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD (p35) and 40 kD (p40) subunits.
The IL-12 p40 monomer shares amino acid sequence homology with the IL-6 receptor. It has been reported that activated PBMC produce a
manyfold excess of IL-12 p40 monomer over the bioactive p70 heterodimer. The IL-12 p40 monomer has been reported to inhibit binding of
IL-12 p70 to the IL-12 receptor, but with 20X less effectiveness than the IL-12 p70 homodimer. Recombinant human IL-12 p70 (Cat. No.
554613) is supplied as a frozen liquid comprised of 0.22 μm sterile-filtered aqueous buffered solution, containing bovine serum albumin and
glycerol, with no preservatives. Purity is ≥ 95% as determined by non-reducing SDS-PAGE, and an absorbance assay based on the
Beers-Lambert Law. The endotoxin level is ≤ 0.1 ng per μg of human IL-12 p70, as measured in a chromogenic LAL assay.


Recombinant Human IL-12 (p70) Preparation and Storage:

Store product at -80°C prior to use or for long term storage of stock solutions.
Rapidly thaw and quick-spin product prior to use.
Avoid multiple freeze-thaws of product.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.


Recombinant Human IL-12 (p70) Suggested Companion Products

Catalog Number Name Size Clone
555065 Purified Rat Anti-Human IL-12 p70 0.5 mg 20C2
554660 Biotin Mouse Anti-Human IL-12 (p40/p70) 0.5 mg C8.6
555171 Human IL-12 (p40) ELISA Set 20 plates (none)
555183 Human IL-12 (p70) ELISA Set 20 plates (none)
551116 Human IL-12 (p40) ELISA Kit II 2 plates (none)
559258 Human IL-12 (p70) ELISA Kit 2 plates (none)

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