產品名稱:PE 小鼠抗大鼠 CD45 抗體;PE Mouse Anti-Rat CD45
中文名稱:PE 小鼠抗大鼠 CD45抗體
英文名稱:PE Mouse Anti-Rat CD45
PE Mouse Anti-Rat CD45 產品介紹:
Material Number: 554878 Alternate Name: Leukocyte Common Antigen Size: 0.2 mg Concentration: 0.2 mg/ml Clone: OX-1 Immunogen: Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes Isotype: Mouse (BALB/c) IgG1, κ Reactivity: QC Testing: Rat Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PE Mouse Anti-Rat CD45 Description:
The OX-1 antibody reacts with all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed by gel filtration chromatography. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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