產品名稱:Purified NA/LE 小鼠抗大鼠 CD28 抗體;Purified NA/LE Mouse Anti-Rat CD28
中文名稱:Purified NA/LE 小鼠抗大鼠 CD28 抗體
英文名稱:Purified NA/LE Mouse Anti-Rat CD28
Purified NA/LE Mouse Anti-Rat CD28 產品介紹:
Material Number: 554993 Size: 0.5 mg Concentration: 1.0 mg/ml Clone: JJ319 Immunogen: Rat CD28-transfected cell line Isotype: Mouse (BALB/c) IgG1, κ Reactivity: QC Testing: Rat Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. Purified NA/LE Mouse Anti-Rat CD28 Description:
The JJ319 antibody reacts with CD28, which is expressed on virtually all T lymphocytes bearing αβ T-cell receptors (TCR), on most γδ TCR-bearing T cells, and on a subset of NK cells. In the thymus, CD28 expression is developmentally regulated during the maturation of αβ TCR-bearing T cells. CD28 is a costimulatory receptor required for activation of T cells; its ligands include CD80 (B7-1) and CD86 (B7-2). Soluble JJ319 mAb costimulates the proliferative responses and IL-2 production of CD4+ and CD8+ T cells activated by anti-αβ-TCR mAb R73 (Cat. no. 554910). The alternate anti-rat CD28 mAb JJ316 (Cat. No. 554992) is capable of directly stimulating T cells in vitro and in vivo.
Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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